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  • Anti -SCN4B Rabbit pAb

    货号:GB111596

    品牌:Servicebio

    价格:¥650

    规格: 100 μl

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    Product Information

     

    Description
    SCN4B rabbit polyclonal
    Protein full name
    Sodium channel subunit beta-4
    Synonyms
    Scn4b, Gm1471, sodium channel, voltage gated, type IV beta subunit, voltage-gated, LQT10, Navbeta4, ATFB17
    Immunogen
    Recombinant protein corresponding to
    Mouse SCN4B
    Isotype
    IgG
    Purity
    Affinity purification
    Subcellular location
    Plasma membrane
    Uniprot ID

     


     

    Applications

     

    Applications
    Species
    Dilution
    Positive Tissue
    IHC
    Mouse, Rat
    1: 1000-1: 2000
    brain, heart

     


     

    Background
     

    The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. 

     


     

    Images

     


    Immunohistochemistry analysis of paraffin-embedded mouse brain using SCN4B (GB111596) at dilution of 1: 2000
     

    Immunohistochemistry analysis of paraffin-embedded rat heart using SCN4B (GB111596) at dilution of 1: 2000
     

     


     

    Storage

     

    Storage
    Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
    Storage Buffer
    PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.
     

     

    NOTE: This product is intended for research only.

     

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