The gene catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans . The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis.
Western blot analysis of UGDH (GB111595)
at dilution of 1:1000
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: Mouse heart tissue lysate
Lane 4: Mouse ovary tissue lysate
Lane 5: Rat heart tissue lysate
Lane 6: Rat stomach tissue lysate
NOTE: This product is intended for research only.