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  • Anti -Hsp47 Rabbit pAb

    货号:GB111425

    品牌:Servicebio

    价格:¥650

    规格: 100 μl

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    Product Information

     

    Description
    Hsp47 rabbit polyclonal
    Protein full name
    Serpin H1
    Synonyms
    47 kDa heat shock protein, Collagen-binding protein, Colligin, Serine protease inhibitor J6, Serpinh1, Cbp1, Hsp47
    Immunogen
    KLH conjugated Synthetic peptide
    corresponding to Mouse Hsp47
    Isotype
    IgG
    Purity
    Affinity purification
    Subcellular location
    Cytoplasm
    Uniprot ID

     


     

    Applications

     

    Applications
    Species
    Dilution
    Positive Tissue
    IHC
    Human, Mouse
    1: 1000-1: 2000
    colon cancer, ovary cancer
    IF
    Human, Mouse
    1: 500-1: 1000
    colon cancer, skin, placenta

     


     

    Background

     

    Hsp47, also known as colligin and gp46, is an ER-resident collagen-specific stress glycoprotein involved in the synthesis and assembly of varoius collagens as a molecular chaperone. Hsp47 is a member of the serpin superfamily, but localizes to the ER via binding of its C-terminal RDEL sequence to KDEL receptors in the ER. Hsp47 binds procollagen co-translationally as it enters the ER, and dissociates prior to its secretion.

         


     

    Images

     




    Immunohistochemistry analysis of paraffin-embedded human colon cancer using Hsp47 (GB111425) at dilution of 1: 2000

    Immunohistochemistry analysis of paraffin-embedded human ovary cancer using
    Hsp47 (GB111425) at dilution of 1: 2000

    Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using Hsp47 (GB111425) at dilution of 1: 800

    Immunofluorescent analysis of paraformaldehyde-fixed mouse skin using
    Hsp47 (GB111425) at dilution of 1: 800

    Immunofluorescent analysis of paraformaldehyde-fixed mouse placenta using Hsp47 (GB111425) at dilution of 1: 800

     


     

    Storage

     

    Storage
    Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
    Storage Buffer
    PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

     


     

    NOTE: This product is intended for research only.

     

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